Instinct Bio Technical Company Holdings Inc. (Nasdaq: BIOT) announced on July 30, 2026, that its subsidiaries have entered into a Memorandum of Agreement with Invitrx Therapeutics, Inc. (INVITRX) to expand the GENREVER cosmetic brand into the United States and support regenerative medicine projects in Indonesia. The collaboration builds on a six-year commercial relationship in which Instinct Bio sourced raw materials from INVITRX.
Under the proposed collaboration, Instinct Bio will license the GENREVER trademark, and its subsidiary Artisans Production will contribute proprietary formulations and raw materials. INVITRX is expected to manufacture GENREVER products at its U.S. GMP manufacturing facility. The parties intend to position GENREVER as a premium Japanese cosmetics brand in the U.S. market, pending regulatory approvals.
In Indonesia, the collaboration aims to supply concentrated exosomes and conditioned media for planned clinics and an in-hospital cell processing center. This initiative seeks to establish a localized regenerative medicine platform in a rapidly growing healthcare market. The parties will evaluate opportunities while progressing through regulatory and commercial milestones.
Tomoki Nagano, CEO of Instinct Bio, stated: 'This collaboration represents an important step in our strategy to expand Instinct Bio’s international platform. By bringing together the GENREVER brand, Artisans Production’s proprietary formulations and INVITRX’s U.S. GMP manufacturing capabilities, we believe we are creating a strong foundation for future growth in both the United States and Southeast Asia.'
The MOA sets a framework for negotiating definitive agreements, with no assurance that the proposed initiatives will be completed. The collaboration highlights Instinct Bio's commitment to regenerative medicine and longevity technologies, while INVITRX brings its GMP manufacturing expertise and cell-derived biological materials.
Instinct Bio is a biotechnology company focused on regenerative medicine and advanced therapeutic platforms, listed on Nasdaq under BIOT. More information is available at https://instinct-biot.com/. INVITRX is a U.S.-based biotechnology company operating a GMP facility and supplying concentrated exosomes and conditioned media.


